Leveraging Open Datasets from the Allen Brain Observatory for Computational Neuroscience
Organizers
Saskia de Vries | Allen Institute, Seattle, USA
Josh Siegle | Allen Institute, Seattle, USA
Abstract
This program will teach participants how to take advantage of Allen Brain Observatory data, via hands-on tutorials and a showcase of scientific talks. Our publicly available datasets include both 2-photon calcium imaging and dense electrophysiological recordings from the visual cortex of awake mice. The data has been collected under highly standardized conditions using rich visual stimulus sets, to facilitate comparisons across experiments and recording modalities. These readily accessible, well-documented datasets can be used by the community to test new analysis methods, evaluate models of neural function, or generate ideas for targeted studies.
We will begin by introducing participants to the scientific motivation and technical details of the Allen Brain Observatory experiments. We will then demonstrate how to use the AllenSDK, an open-source Python library that provides a convenient interface for data retrieval and analysis. A hands-on tutorial will prepare participants to dive in to their own analysis of these neural recordings. In the second half of the workshop, invited speakers from both inside and outside the institute will provide examples of work that has already been carried out with Allen Brain Observatory data.
Schedule
time (CEST) |
|
14:00 | Saskia de Vries | Allen Institute, Seattle, USA 2-photon dataset tutorial |
15:30 | Josh Siegle | Allen Institute, Seattle, USA Neuropixels dataset tutorial |
17:00 | 30 min break |
17:30 | Michael Buice | Allen Institute, Seattle, USA A large-scale, standardized physiological survey reveals functional organization of the mouse visual cortex. |
18:00 | Huijeong Jeong | KAIST, Daejeon, South Korea Hippocampal-visual cortical coupling during offline states |
18:30 | Xiaoxuan Jia | Allen Institute, Seattle, USA Distributed cortical subnetworks revealed with multi-area electrophysiological recordings |
19:00 | Rob Kass | Carnegie Mellon University, Pittsburgh, USA Statistical assessment of interactions among multiple brain regions from Neuropixels recordings |
19:30 | 30 min break |
20:00 | Stefan Mihalas | Allen Institute, Seattle, USA Is the role of noise to help generalization? |
20:30 | Yann Sweeney | Imperial College London, UK Population coupling predicts the plasticity of stimulus responses in cortical circuits |
21:00 | Josh Siegle | Allen Institute, Seattle, USA Comparing neural responses in mouse visual cortex acquired with electrophysiology and two-photon imaging |
21:30 | Panel discussion with all speakers |
22:00 | End |