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Bernstein Center (BCCN) Göttingen

2nd Funding Period: Cooperative Dynamics and Adaptivity

The mission of the BCCN Göttingen is to uncover, quantify, and model the role of cooperative dynamics in adaptive neuronal computation. To characterize cooperative neuronal processes on various levels ranging from subcellular properties through sensory systems to cognition and behavioral control the BCCN Göttingen will tackle important problems such as: How do supramolecular complexes and interacting intracellular structures contribute to adaptive single neuron computation? How do the collective dynamics of biological neural networks drive processes of adaptive coding and learning? How do dynamical interactions within sets of brain areas mediate the flexible use of neuronal processing resources and strategies? How can the interaction between neuronal motor control and high-dimensional movement kinematics generate smooth, precise, and effective hand and limb movements?

On the theoretical side the BCCN Göttingen will approach these questions by a common methodology for dissecting the dynamical and statistical laws of interacting multi-component systems that combines advanced data analysis and biologically detailed as well as abstract mathematical modeling approaches. Experimentally the center will study these questions in biological model systems ranging from in vitro preparations of neuronal cells and circuits, through genetically highly accessible sensory systems such as the drosophila and mouse auditory system, to experimental assays of neocortical function in humans and non-human primates. Technological and clinical applications of the results will be pursued in collaboration with the industrial, clinical and rehabilitation partners of the Bernstein Center Göttingen and in coordination with Göttingen’s Bernstein Focus Neurotechnology.

The BCCN Göttingen integrates projects at the following research institutions:

  • Georg August Universität Göttingen
  • Universitätsmedizin Göttingen
  • Max Planck Institute for Dynamics and Self-Organization
  • Max Planck Institute for Experimental Medicine
  • Max Planck Institute for Biophysical Chemistry
  • German Primate Center

Industry partner:

  • Otto Bock Healthcare GmbH